MoviPrep FAQs

Frequently asked questions about the MoviPrep experience

What is MoviPrep?

MoviPrep is a low-volume, polyethylene glycol (PEG)–based osmotic colonoscopy preparation that is proven to effectively cleanse your colon, allowing your doctor to detect and remove abnormal growths that may otherwise grow into cancer.

Is MoviPrep widely used?

Yes. In fact, MoviPrep has been prescribed nearly 8 million times in the United States since 2006.

How much solution will I have to drink with MoviPrep?

Unlike traditional colonoscopy preps that require you to drink 4 liters of PEG, MoviPrep requires you to drink 2 liters of PEG and an additional 1 liter of the clear liquid of your choice.

Can I take MoviPrep with a split dose?

Yes. MoviPrep is the first PEG-based prep approved by the FDA for a PM|AM Split Dosing regimen. Research shows that this regimen—in which you take the first dose of your prep the day before the procedure and complete the prep on the day of the procedure—improves the overall effectiveness and tolerability of the colonoscopy prep. Of course, MoviPrep is also approved for an evening-only dosing regimen. Ultimately, you should follow your doctor's dosing instructions.

What does MoviPrep taste like?

MoviPrep is lemon flavored. Admittedly, however, it may not taste like a glass of fresh-squeezed lemonade. What is important is that MoviPrep effectively cleanses your colon so your doctor can detect and remove abnormal growths during a colonoscopy.

Who should not take MoviPrep?

Do not take MoviPrep if your healthcare provider has told you that you have:

  • A blockage in your intestine (bowel obstruction)
  • An opening in the wall of your stomach or intestine (bowel perforation)
  • Problems with food and fluid emptying from your stomach (gastric retention)
  • A very dilated intestine (toxic megacolon)
  • An allergy to any of the ingredients in MoviPrep

Indication for MOVIPREP

MOVIPREP® (PEG-3350, sodium sulfate, sodium chloride, potassium chloride, sodium ascorbate and ascorbic acid for oral solution) is an osmotic laxative indicated for cleansing of the colon as a preparation for colonoscopy in adults 18 years of age or older.

Important Safety Information about MOVIPREP

  • Do not take MOVIPREP® (PEG-3350, sodium sulfate, sodium chloride, potassium chloride, sodium ascorbate and ascorbic acid for oral solution) if you have a gastrointestinal (GI) obstruction (a blockage in your bowel), bowel perforation (an opening in the wall of your stomach or intestine), gastric retention (problems with food and fluid emptying from your stomach), ileus (bowel muscle unable to move stomach contents), toxic colitis (damage to the thickness of the intestinal wall) or toxic megacolon (an extremely dilated or distended colon with fever and/or abdominal pain at times), or if you have a known allergy to MOVIPREP or any of its components.
  • It is important to drink sufficient liquids before, during, and after the use of MOVIPREP. Liquid and blood salt changes can lead to serious side effects including abnormal heartbeats, seizures, and kidney problems. Talk to your doctor before taking MOVIPREP if you take any medications that increase the risk of blood salt abnormalities or if you have known or suspected low blood salt (sodium) level (hyponatremia).
  • If you have kidney problems or if you take medication that affects kidney function, talk to your doctor before taking MOVIPREP.
  • If you have suspected bowel blockage or a suspected opening in the wall of your stomach or intestine, talk to your doctor before taking MOVIPREP.
  • Talk to your doctor before taking MOVIPREP if you have problems swallowing, if you have gastric reflux, or if you are predisposed to aspiration.
  • If you have a condition that destroys red blood cells called glucose-6-phosphate dehydrogenase (G6PD) deficiency, talk to your doctor before taking MOVIPREP.
  • Please be advised that MOVIPREP contains 131 mg of phenylalanine per treatment.
  • If you are pregnant or planning to become pregnant, talk to your doctor before taking MOVIPREP.
  • In clinical studies with MOVIPREP, the most common side effects for split dosing were malaise (feeling uneasy), nausea, stomach (abdominal) pain, vomiting, and upper stomach pain. The most common side effects for evening only dosing were stomach swelling (abdominal distension), anal discomfort, thirst, nausea, stomach (abdominal) pain, sleep disorder, rigors (body shakes), hunger, malaise (feeling uneasy), vomiting, and dizziness.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch/ or call 1-800-FDA-1088.

For product information, adverse event reports, and product complaint reports, please contact:

Salix Product Information Call Center
Phone: 1-800-508-0024
Fax: 1-510-595-8183
Email: salixmc@dlss.com

Please click here for complete Prescribing Information for MOVIPREP. 

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