What Is the Colon?

The colon

The colon is the final segment of the digestive tract where waste is formed into solid stool. The colon completes the digestive process and prepares waste to leave the body.

Picture of the colon and digestive system

As the final segment of the digestive tract, the colon forms waste into solid stool.

After you swallow food, it travels from the mouth through the esophagus to the stomach. Once broken down, the food moves from the stomach to the small intestine. The small intestine takes the nutrients from food, and the remaining indigestible portion moves into the colon. The colon helps prepare this waste until the next bowel movement removes it from the body.

The colon is difficult to examine because of its shape and location in the body. But, when the colon needs to be examined, the best way for your doctor to do so is with a colonoscopy. This procedure allows your doctor to inspect the walls of your colon for abnormal growths (colon polyps) that may turn into cancer if they are not detected and removed.

Indication for MOVIPREP

MOVIPREP® (PEG-3350, sodium sulfate, sodium chloride, potassium chloride, sodium ascorbate and ascorbic acid for oral solution) is an osmotic laxative indicated for cleansing of the colon as a preparation for colonoscopy in adults 18 years of age or older.

Important Safety Information about MOVIPREP

  • Do not take MOVIPREP® (PEG-3350, sodium sulfate, sodium chloride, potassium chloride, sodium ascorbate and ascorbic acid for oral solution) if you have a gastrointestinal (GI) obstruction (a blockage in your bowel), bowel perforation (an opening in the wall of your stomach or intestine), gastric retention (problems with food and fluid emptying from your stomach), ileus (bowel muscle unable to move stomach contents), toxic colitis (damage to the thickness of the intestinal wall) or toxic megacolon (an extremely dilated or distended colon with fever and/or abdominal pain at times), or if you have a known allergy to MOVIPREP or any of its components.
  • It is important to drink sufficient liquids before, during, and after the use of MOVIPREP. Liquid and blood salt changes can lead to serious side effects including abnormal heartbeats, seizures, and kidney problems. Talk to your doctor before taking MOVIPREP if you take any medications that increase the risk of blood salt abnormalities or if you have known or suspected low blood salt (sodium) level (hyponatremia).
  • If you have kidney problems or if you take medication that affects kidney function, talk to your doctor before taking MOVIPREP.
  • If you have suspected bowel blockage or a suspected opening in the wall of your stomach or intestine, talk to your doctor before taking MOVIPREP.
  • Talk to your doctor before taking MOVIPREP if you have problems swallowing, if you have gastric reflux, or if you are predisposed to aspiration.
  • If you have a condition that destroys red blood cells called glucose-6-phosphate dehydrogenase (G6PD) deficiency, talk to your doctor before taking MOVIPREP.
  • Please be advised that MOVIPREP contains 131 mg of phenylalanine per treatment.
  • If you are pregnant or planning to become pregnant, talk to your doctor before taking MOVIPREP.
  • In clinical studies with MOVIPREP, the most common side effects for split dosing were malaise (feeling uneasy), nausea, stomach (abdominal) pain, vomiting, and upper stomach pain. The most common side effects for evening only dosing were stomach swelling (abdominal distension), anal discomfort, thirst, nausea, stomach (abdominal) pain, sleep disorder, rigors (body shakes), hunger, malaise (feeling uneasy), vomiting, and dizziness.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch/ or call 1-800-FDA-1088.

For product information, adverse event reports, and product complaint reports, please contact:

Salix Product Information Call Center
Phone: 1-800-508-0024
Fax: 1-510-595-8183
Email: salixmc@dlss.com

Please click here for complete Prescribing Information for MOVIPREP. 

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