What Is a Colonoscopy Prep?

The colonoscopy prep

During a colonoscopy, your doctor carefully examines the walls and lining of your digestive tract, looking for any subtle abnormalities that could be a sign of something more serious. To ensure a thorough examination, your colon must be completely emptied of all waste material. To accomplish this, your doctor will prescribe a colonoscopy preparation (also known as a colonoscopy prep or bowel prep) before your exam.

The colonoscopy preparation works by causing diarrhea so your body can flush out all solid waste, giving your doctor a clear view of your entire large intestine and colon. Colonoscopy is the gold standard for colorectal cancer screening, but your doctor may also prescribe a bowel prep for a number of procedures, including

Be sure you understand your physician's instructions for the colonoscopy prep—a complete prep is key to a successful colonoscopy.

There are many varieties of prescription colonoscopy prep medications available that use different methods to flush out the colon, and their safety and efficacy have been established in clinical trials. Some people use over-the-counter (OTC) laxatives to prepare for a colonoscopy, but these are not FDA approved for colonoscopy prep. Their safety and efficacy have not been established in clinical trials.

The importance of a thorough colonoscopy prep

Colonoscopy is a potentially lifesaving procedure that requires a complete colonoscopy prep. Solid matter can block your doctor's view of the walls of your colon—potentially resulting in missed lesions or polyps, which can grow into cancer if they are not removed. An incomplete bowel prep can also result in cancelled appointments and an increased risk of complications. To learn more about why a colonoscopy prep is important, read about colon cancer.

Indication for MOVIPREP

MOVIPREP® (PEG-3350, sodium sulfate, sodium chloride, potassium chloride, sodium ascorbate and ascorbic acid for oral solution) is an osmotic laxative indicated for cleansing of the colon as a preparation for colonoscopy in adults 18 years of age or older.

Important Safety Information about MOVIPREP

Do not take MOVIPREP® (PEG-3350, sodium sulfate, sodium chloride, potassium chloride, sodium ascorbate and ascorbic acid for oral solution) if you have a gastrointestinal (GI) obstruction (a blockage in your bowel), bowel perforation (an opening in the wall of your stomach or intestine), gastric retention (problems with food and fluid emptying from your stomach), ileus (bowel muscle unable to move stomach contents), toxic colitis (damage to the thickness of the intestinal wall) or toxic megacolon (an extremely dilated or distended colon with fever and/or abdominal pain at times), or if you have a known allergy to MOVIPREP or any of its components.

It is important to drink sufficient liquids before, during, and after the use of MOVIPREP. Liquid and blood salt changes can lead to serious side effects including abnormal heartbeats, seizures, and kidney problems. Talk to your doctor before taking MOVIPREP if you take any medications that increase the risk of blood salt abnormalities or if you have known or suspected low blood salt (sodium) level (hyponatremia).

If you have kidney problems or if you take medication that affects kidney function, talk to your doctor before taking MOVIPREP.

If you have suspected bowel blockage or a suspected opening in the wall of your stomach or intestine, talk to your doctor before taking MOVIPREP.

Talk to your doctor before taking MOVIPREP if you have problems swallowing, if you have gastric reflux, or if you are predisposed to aspiration.

If you have a condition that destroys red blood cells called glucose-6-phosphate dehydrogenase (G6PD) deficiency, talk to your doctor before taking MOVIPREP.

Please be advised that MOVIPREP contains 131 mg of phenylalanine per treatment.

If you are pregnant or planning to become pregnant, talk to your doctor before taking MOVIPREP.

In clinical studies with MOVIPREP, the most common side effects for split dosing were malaise (feeling uneasy), nausea, stomach (abdominal) pain, vomiting, and upper stomach pain. The most common side effects for evening only dosing were stomach swelling (abdominal distension), anal discomfort, thirst, nausea, stomach (abdominal) pain, sleep disorder, rigors (body shakes), hunger, malaise (feeling uneasy), vomiting, and dizziness.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch/ or call 1-800-FDA-1088.

For product information, adverse event reports, and product complaint reports, please contact:

Salix Product Information Call Center
Phone: 1-800-508-0024
Fax: 1-510-595-8183
Email: salix@medcomsol.com

Please see complete Prescribing Information for MOVIPREP. pdf icon

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